Calorie Restriction = Extended Lifespan

What You Need to Know about Caloric Restriction

Caloric Restriction (CR), a significant, sustained reduction of caloric intake from baseline levels, is the most thoroughly and successfully researched method for lifespan and healthspan extension in a broad range of animals and non-human primates.

In many cases, the reduction of caloric intake by 30 to 40 percent in animal models has resulted in longevity increases by 40 percent or more.

Although there is not yet direct human evidence of lifespan extension in humans from CR, results of the NIA-funded CALERIE study have shown significant reductions in risk factors for disease (cardiovascular disease, diabetes, some cancers), from moderate CR.

CR in humans reduces fasting insulin levels and lowers resting body temperature, which are two biomarkers for aging reversal.

Although CR has classically been defined as a long-term 30 to 40 percent reduction in calories, some CR health benefits in humans have been observed at less-restrictive caloric reductions (16 to 25 percent) over short time periods (weeks to months).

CR may work by reducing oxidative damage, increasing cellular repair, lowering production of inflammatory cytokines, or by hormesis, a mild stress that may stimulate cellular protection.

Several compounds may mimic the effects of CR without requiring a reduction in calories; these include resveratrol, metformin, green tea polyphenols, aspirin, pyrroloquinoline quinone (PQQ), and branched-chain amino acids.

Maintaining a dramatically reduced caloric intake over the long-term can be very demanding. Few people are willing to reduce their caloric consumption by the 30 to 40 percent to meet the classic CR definition,111 and even the less restrictive protocols (16-25%) used in human interventions have not been met with full compliance. The search for an alternative or complement to CR has involved the identification or development of compounds that mimic some of the physiological or gene-expression changes associated with CR, without the requirement of lowered caloric intake or loss of body weight. While many compounds can be broadly interpreted as CRMs, a more focused definition of CRM would be a compound or intervention that mimics the metabolic, hormonal, or physiological effects of CR without reducing long-term food intake, while stimulating maintenance and repair processes, and producing CR-like effects on longevity and reduction of age-related disease.

Several compounds have been investigated as CRMs, with encouraging preliminary results in animal models. Tetrahydrocurcumin (a curcumin metabolite) and green tea polyphenols have both demonstrated increases in average and maximum lifespans in mice.  The effects were observed when the mice received treatments by month 13 (if given later in life, the treatments had no effect on lifespan), and in the case of green tea extract, the treatment had no effect on body weight. An investigation of ginkgo biloba on cognitive behavior in male Fischer rats revealed an unexpected, statistically significant increase in average lifespan when compared to controls (26.4 vs. 31.0 months).The NIA Aging Intervention Testing program, a multi-center study on longevity-enhancing compounds, has already identified life-extending or CR mimetic activities in rapamycin and aspirin in rodents, and is currently testing other potential compounds including medium chain triglycerides, caffeic acid esters, and curcumin.

Stress-induced plant compounds can stimulate stress responses in other species, this cross-species hormesis is called xenohormesis. Xenohormesis may have evolved as an early warning in animals about impending changes in the environment (such as scarcities in the food supply), allowing them to adapt accordingly. The most familiar of these stress-inducing compounds is resveratrol, well-known for its presence in grape skin, but present at detectable levels in several plant species. Resveratrol simulates caloric restriction in the absence of actual nutrient deficiency by activating sirtuins (SIRT1 is the human homolog), and has been shown to increase lifespan in fungi, nematodes, flies, fish, and mice SIRT1 also suppresses NF-kB (and the inflammatory cytokines and enzymes NF-kB activates), lending resveratrol anti-inflammatory activity in cell culture and animal models.  High-dose resveratrol reduced IGF-1 levels in healthy human volunteers, a chemopreventive activity that is also associated with CR. Pterostilbene, a methylated analogue of resveratrol from blueberries, similarly attenuates inflammation in a CR-like manner, reducing NF-kB signaling and COX-2 activities in cell culture.

Other plant-derived polyphenolic compounds (such as catechins, curcumin, or flavonoids) may also have xenohormesis activities as well; it has been suggested that the majority of health benefits from plant phytochemical consumption might not be from their antioxidant properties, but rather by a CR-like modulation of stress-response pathways. Fisetin, quercetin, proanthocyanidins, and theaflavins are examples of compounds that have inherent chain-breaking antioxidant chemistries, but appear to exert profound health effects unrelated to their ability to quench free radicals. Fisetin and quercetin have both been shown to stimulate SIRT, a central activity of CR. In vitro, fisetin, like CR, reduced mTOR signaling, Nf-kB activation and COX-2 gene expression, and activated antioxidative and detoxifying gene pathways (Nrf2). Fisetin has also been shown to increase lifespan in Saccharomyces 136 and Drosophila.Quercetin, in addition to proanthocyanidins from grape seed, have also been shown to reduce the production of inflammatory cytokines, and the expression of vascular endothelial growth factor (VEGF), which may prevent tumors from recruiting blood vessels. This same chemoprotective activity has been observed in rats under CR. Theaflavins are flavan-3-ols from black tea that are produced during the oxidation (fermentation) of tea leaves. Aside from their suppression of NF-kB and inflammatory cytokines in vitro and in mice and their induction of apoptosis in cancer cells, theaflavins also stimulate the longevity factor Forkhead box 1 (FOXO1) in invertebrate and mammalian cells.

Nicotinamide riboside is another naturally-occurring compound that may act as a CRM. It is a source of vitamin B3 and a precursor for nicotinamide adenine dinucleotide (NAD+), a molecule involved in a wide array of biological processes. NAD+, one of the important biologically active forms of NAD, is necessary for the activation of proteins called sirtuins, including SIRT1, that regulate cellular metabolism and DNA transcription. NAD+ levels are known to decrease with age, resulting in lower sirtuin activity. This may contribute to dysfunction in cell nuclei and mitochondria, and to a range of age-related disorders. Like calorie restriction and exercise, nicotinamide riboside can increase NAD+ levels and SIRT1 activation, and may be able to prevent or reverse age-related mitochondrial and metabolic dysfunction and disease in yeast cells, nicotinamide riboside supplementation raised NAD+ levels and increased lifespan without calorie restriction. Even in mice on a high-fat diet, nicotinamide riboside supplementation was found to raise NAD+ levels and SIRT1 activity, and was associated with positive metabolic effects, including less weight gain, improved exercise performance, and decreased liver fat.179

The glucoregulatory agent metformin can produce many of the gene expression changes found in mice on long-term caloric restriction, in particular, it can decrease the expression of chaperones; a set of proteins which, in addition to their other functions, can reduce apoptosis (self-destruction of damaged or malignant cells) and promote tumorgenesis. Metformin has increased mean lifespan in the worm C elegans.144 Along with the related anti-diabetic biguanide drugs phenformin and buformin, metformin extended the mean life span of mice by up to 37.9 percent and their maximum life span by up to 26 percent in multiple studies (reviewed in) while significantly decreasing the incidence and size of mammary tumors. These effects on spontaneous tumor incidence, however, were limited to female animals.  Metformin’s CR-like effects are possibly due to influence on insulin or IGF-1 signaling. This mechanism may also explain the lifespan extension properties of the glucoregulatory herb Cinnamomum cassia (cinnamon bark) in the C. elegans.

Numerous studies have found that metformin, which can induce a calorie restriction-like state, activates a critical enzyme called adenosine monophosphate-activated protein kinase (AMPK). This enzyme, which affects glucose metabolism and fat storage, has been called a “metabolic master switch” because it controls numerous pathways related to extracting energy from food and storing and distributing that energy throughout the body.

Gynostemma pentaphyllum (G. pentaphyllum) is used in Asian medicine to promote longevity.163 Its longevity effects appear to be due, in part, to its ability to activate AMPK.161 Studies of G. pentaphyllum supplementation in humans demonstrate effects also found in calorie restriction, such as improved glucose metabolism, and reduced body weight, abdominal fat, and overall fat.  Other studies found that G. pentaphyllum significantly improves insulin sensitivity, a mechanism also observed in studies of caloric restriction.

Trans-tiliroside is an extract obtained from rose hips that has been used for nearly a century to treat a variety of conditions, including cardiovascular disease, diabetes, and inflammatory diseases.  Trans-tiliroside’s effects appear to be due in part to its ability to activate AMPK. Caloric restriction and exercise are both efficient activators of AMPK, as this enzyme pathway is stimulated when energy demand exceeds supply.

In a clinical trial, rose hip extract supplementation in 32 overweight individuals resulted in significantly less total abdominal fat, abdominal visceral fat, body weight, and body mass index by the end of the 12-week trial compared with those who received placebo. Numerous preclinical trials have shown that trans-tiliroside and its derivatives boost AMPK signaling. In a mouse study, administration of a rose hips extract significantly reduced dangerous after-meal glucose spikes and inhibited weight gain, particularly abdominal fat deposition.

Fish oil, while not a CRM, appears to increase the efficacy of CR at preventing free radical damage; fish oil feeding with 40% CR in mice demonstrated synergistic reductions in thiobarbituric acid reactive substances (TBARS, a marker of lipid peroxidation), and was more effective at reducing inflammatory markers (COX-2 and iNOS expression) that CR or fish oil alone. 

The branched-chain amino acids (leucine, isoleucine, and valine) exhibit several CR-like properties, particularly related to mitochondrial biogenesis. Leucine increased mitochondrial mass in cultured human myocytes (muscle cells), and activated genes associated with CR (PGC-1α and SIRT-1).  Elevations in CR gene expression were observed in mouse cardiomyocytes using a mixture of all three BCAAs.151 The BCAAs have also extended lifespan in Saccharomyces as well as in mice, when supplied above normal dietary levels. Similarly, pyrroloquinoline quinone (PQQ), a bacterial electron carrier and cofactor for several bacterial enzymes (and at least one mammalian enzyme increased mitochondrial DNA content and stimulated oxygen respiration (both indicative of biogenesis) in cultured mouse hepatoma cells through the activation of the CR gene PGC.

 

 


Disclaimer and Safety Information

This information (and any accompanying material) is not intended to replace the attention or advice of a physician or other qualified health care professional. Anyone who wishes to embark on any dietary, drug, exercise, or other lifestyle change intended to prevent or treat a specific disease or condition should first consult with and seek clearance from a physician or other qualified health care professional. Pregnant women in particular should seek the advice of a physician before using any protocol listed on this website. The protocols described on this website are for adults only, unless otherwise specified. Product labels may contain important safety information and the most recent product information provided by the product manufacturers should be carefully reviewed prior to use to verify the dose, administration, and contraindications. National, state, and local laws may vary regarding the use and application of many of the treatments discussed. The reader assumes the risk of any injuries. The authors and publishers, their affiliates and assigns are not liable for any injury and/or damage to persons arising from this protocol and expressly disclaim responsibility for any adverse effects resulting from the use of the information contained herein.

The protocols raise many issues that are subject to change as new data emerge. None of our suggested protocol regimens can guarantee health benefits. The publisher has not performed independent verification of the data contained herein, and expressly disclaim responsibility for any error in literature.

Robots And Our Future!

Ray Kurzweil is the Mind Behind the Theory of The Singularity

Futurist and inventor, Ray Kurzweil, is the mind behind the theory of the singularity taking place by 2045, the point when humans multiply our effective intelligence a billionfold by merging with the intelligence we have created. He is attending the festival this year with PHD in order to appear on stage and film elements of a new film the media agency is making around the topic of AI. It is also using the presence of Kurzweil to launch a book on the topic, appropriately named ‘Merge’.

“It’s an optimistic group that welcomes the future as I do,” says Kurzweil when asked what he thinks of the festival. He is sitting quietly on a large deep chair in the middle of the grand lobby of the JW Marriott on Le Croisette having flown in just that morning from the US. He is clearly tired when The Drum greets him but soon warms up while discussing the topic he has spent his professional life leading – the transformational power of technology on people and language.

Asked about his views on the advancement of advertising and communications as a result of technological progress, Kurzweil immediately turns to how useful advertising can be now as it becomes more focused through understanding online user interests.

“Advertising is really blending in with other forms of communication and that is something that people welcome because it is topics that they have an interest in,” he says.

“Brands are very important because we need to trust information. Not everything on the internet can be relied on so we use brands as a way of knowing what is reliable,” he explains, before later adding that AI can help ensure people are treated as individuals rather than a mass audience being served the same message in unison.

“People will resent wasting their time with messages that don’t agree with them, that are in areas they are not interested in, so AI is going to tell people they are going to like a movie or a song and we appreciate that because it’s usually right and brands have to be associated with good quality information. You can’t sell something that people are not going to like,” he says.

He cites advice his aunt, who was a senior vice president of Doyle Dane and Bernbach (DDB) in New York gave, that trying to advertise a brand that people aren’t going to like is the quickest way to kill it: “You have to be selling something that is worthwhile and then people will appreciate the message and it’s more and more important that people can trust in an era that is filled with misinformation.”

He goes on to claim that “language is at the heart of human intelligence” and says that the understanding of human language cannot be faked when asked what technological developments are exciting him currently.

“To really understand language you really have to understand human intelligence and knowledge at human levels. That’s what I work on and that is what I think is most exciting but AI keeps doing things that people thought were only the province of human intelligence. Every time AI does something we say ‘that’s not really AI’ and it has been called ‘the set of problems we haven’t solved yet’ but that is getting smaller and smaller.”

He repeatedly states that the dawn of AI is not “an alien invasion from Mars” but a result of human ingenuity and believes that technology will ultimately “go inside our bodies and brains” to aid health and and that the neo-cortex of the human brain will be linked directly to the cloud, taking man’s evolution a step further as technology assists brains to access more knowledge than ever before.

“We are going to connect our neo-cortex to the cloud and add again to the hierarchy and make ourselves smarter and create capabilities we can’t even imagine today. Try explaining language or music or humor to a primate that doesn’t understand those concepts. We’ll create new types of knowledge that we can’t understand today when we increase our neo-cortex wirelessly to the cloud. That’s my vision of the future that’s a 2030 scenario,” he confides.

“If you read my predictions going back to the 80s and 90s, I am always surprised when things I have talked about come true,” he later admits. “Although I write about them I still find them remarkable. People very quickly get used to them. It’s always been that way,” he says, before using the smartphone as an example of something that was mass adopted five years ago and quickly change society.

And it’s the accuracy of such predictions that have made Kurzweil’s name. For all his writings, he is still best known for his prediction of the Singularity, and despite the continued increase in the speed of technological advancements, he says he still stands by his assertion that the artificial intelligence will be able to pass a Turing test 12 years from now, and that the singularity will still happen in 2045 despite the continued debate of others in the field.

“There are more and more developments that support that view. My view has stayed the same, the consensus view of experts and the general public is moving towards me,” he says.

He continues: “There is a growing group of people who think I’m too conservative but I see no reason to change my view. AI is doing more and more things that people said it would never do… by 2029 they will do anything humans can do…

“We make these machines to be smarter and we are already smarter. The idea that we are going to merge with this technology is not radical. We are doing it right now and the typical dystopian futurist movie is the AI versus the brave band of humans fighting for control of humanity. We don’t have one single AI in the world today, we have, on last count around 3 billion. Phones are AIs. They have really empowered the individual. They are getting more and more capable and they will be in 8 billion hands within a few years and they are getting more and more integrated with us and they are starting to go into our bodies and brains and it starts with extreme cases like Parkinson’s patients but that will be ubiquitous in the 2030s. Whether they are inside our bodies or not, they are already extending our capability.”

Finally, when asked about the most accurate depiction of AI he has seen in film, he says that Spike Jonze‘s Oscar-winning ‘Her’ is his favourite, but that he felt the ending was a ‘cop out’ and admits that despite the Terminator being one of the most famous depictions of AI on screen, he has yet to meet its famous director and writer James Cameron.

“He did express an interest in an interview for a series he’s doing but I haven’t met him yet,” he responds casually.

This century, if Kurzweil is correct, humanity is set to evolve and reach a new level of intelligence and expand its horizons to new heights with the aid of intelligence. How marketers will deal with that challenge when they are already struggling to deal with other technological developments appearing at a rapid rate will be a fascinating leap for the industry to deal with. How do you advertise to robots anyway

Add 3 Anti Aging Supplements

Add 3 Anti Aging Supplements to your daily dose! 

(These three work in conjunction with each other and is best when taken together, but not absolutely required).

Keep in mind it is less expensive to order from Anazon.com that Life Extension.  The same great product just lower prices.


1. NAD+ Cell Regenerator™ with Resveratrol

Over 6,000 studies have been published on resveratrol, a compound shown to favorably alter genes that help slow the aging process. In fact, resveratrol triggers some of the same beneficial youthful gene expression activated by calorie restriction.1

Optimized NAD+ Cell Regenerator™ with Resveratrol contains NIAGEN®, a novel nutrient shown to support mitochondrial health and promote longevity pathways. This formula provides 250 mg of NIAGEN® nicotinamide riboside.

Optimized NAD+ Cell Regenerator™ with Resveratrol also contains specific compounds in berries, such as pterostilbene and fisetin, which researchers say work in synergy with resveratrol to “turn on” the body’s own longevity genes.

Note

Due to license restrictions, this product is not for sale to doctors and MLM wholesalers in the USA, Canada or the Philippines.

Click here to order >> http://amzn.to/2s1VB2p

2. AMPK Activator

AMPK Activator is an oral formula that turns on AMPK (adenosine monophosphate-activated protein kinase), an enzyme that serves as the body’s master regulating switch. Increased AMPK activity helps to revitalize aging cells, promote mitochondrial production, and inhibit multiple damaging factors associated with aging. But despite all of the scientific research, supplemental support for youthful AMPK levels has been largely non-existent … until now. The clinically validated combination of ActivAMP® (Gynostemma pentaphyllum) and rose hip plant extracts, provides nutrient support for youthful AMPK levels.

Benefits at a Glance

  • Turns on master switch that revitalizes aging cells
  • Promotes mitochondrial production
  • Inhibits multiple damaging factors associated with aging
  • Optimizes cellular energy production

Revitalizing Aging Cells through AMPK Activation

Found in every cell,1,2 AMPK promotes longevity factors that have been shown to extend life span in numerous organisms.3,4 Increasing AMPK signaling “turns off” many damaging effects of aging, thus enabling cells to return to their youthful vitality.5

Life Extension® scientists have compiled years of research to create AMPK Activator, a specialized dual-extract formulation that supports AMPK activation for health optimization. This natural formula supports AMPK enzymatic activities required to safely support a more youthful cellular environment.

Importance of AMPK Activation

Greater AMPK activation has been shown to help target damaging factors of aging.5 Studies show increased AMPK activity supports reduced fat storage,6-8 new mitochondria production,9 and the promotion of healthy blood glucose and lipids already within normal range.4,10

Gynostemma Pentaphyllum Promotes Longevity and Fights Fat

An extract of the plant Gynostemma pentaphyllum was traditionally used in Asian medicine to promote longevity and scientists now know why — G. pentaphyllum promotes AMPK activation.10,11 In one of many studies showing a wide variety of benefits, researchers documented a 1-inch reduction in abdominal circumference on average in overweight individuals who took 450 mg daily of G. pentaphyllum extract for 12 weeks.8

Rose Hips Provides Metabolic Benefits

Trans-tiliroside, extracted from plants such as rose hips, also boosts AMPK activation, but triggers different downstream metabolic benefits than G. pentaphyllum.12-14 Among its many benefits, a low human equivalent dose of 56 mg daily trans-tiliroside has been shown by researchers in preclinical studies to promote healthy blood glucose levels and body weight already within normal range.15

Life Extension AMPK Activator Capsules, 90 Count

Anti-Aging Discovery That Cannot be Overlooked

Scientists uncovered the cell-energizing effect of AMPK in the 1970s. Since then, an exponential volume of data (over 8,500 published studies) has documented the critical role that activated AMPK plays in maintaining life-sustaining cellular functions.

If you’d like to meaningfully extend your healthy life span, activating your cellular AMPK is critical. This is important because in response to aging, excess calorie consumpt

ion, and/or low levels of physical activity, AMPK activity markedly declines.

You can fight AMPK decline with regular exercise and avoiding excessive calories … but it may not be enough. Our AMPK Activator formula is a targeted way to reverse cellular depletion of the critical AMPK enzyme. Don’t waste another moment — try AMPK Activator today!

This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed and results may vary.


3. pTeroPure®

Pterostilbene

Like resveratrol, pterostilbene belongs to a class of compounds called phytoalexins, which are naturally produced by plants when under attack by pathogens such as bacteria or fungi.

Pterostilbene is a compound structurally similar to resveratrol and can also be found in grapes, blueberries, and other small fruits, as well as the bark of some trees.

In laboratory tests, pterostilbene has shown promise for supporting cardiovascular health, glucose levels that are already within normal range, anti-aging and cognitive function.1-8 It helps improve mitochondrial function and supports healthy metabolic function by activating SIRT1 and mimicking calorie restriction.9,10 It has also shown potential to ease inflammation and support antioxidant activity.4,8

This exciting product is based on a licensed patent from the University of Mississippi and the Agricultural Research Service, which is the principal intramural scientific agency of the U.S. Department of Agriculture. pTeroPure® is the authentic pterostilbene used in clinical studies and is the only material licensed for high-dose application in dietary supplements.Life Extension Pteropure Pterostilbene Vegetarian Capsules, 50 mg, 60 Count

 

DISCLAIMER: THE CONTENT AND INFORMATION CONTAINED AT THIS WEBSITE OR IN THE EBOOKS ARE FOR EDUCATIONAL PURPOSES ONLY. IT MAY NOT BE CONSTRUED AS MEDICAL ADVICE, AND WE DO NOT INTEND FOR THIS INFORMATION TO BE USED TO DIAGNOSE OR PRESCRIBE FORMS OF TREATMENT.

Researchers Turn Ordinary Fibers into Water and Air Purifiers

Researchers Turn Ordinary Fibers into Water and Air Purifiers

 

For centuries, rivers have sustained human civilization.  From the Nile to the Indus, these blue-green and brown waters have been invaluable sources of irrigation.  Unfortunately they are equally convenient for waste disposal.  Over time, cocktails of industrial effluents have caused these rivers to acquire much darker hues.  Fortunately, Prof Juan Hinestroza, fiber science, has created a pollutant-absorbing fiber that could help restore rivers to their former glory.

“I often know what color is in fashion in  the U.S. by looking at a river because some of the chemicals used in manufacturing are thrown into lakes and rivers,” Hinestroza said.  It’s so sad because people have to drink that water.  As a result, what we wanted to do is create a material that could capture pollutants from air and water.

Hinestroza developed the polymer using a process known as cyclodextrin polymerization to coat the surface of a cotton fabric.  Polymerization is the process of reacting molecules together in a chemical reaction to form polymers, large molecules of repeated subunits.  The resultant material is capable of  filtering a variety of contaminants,  including Styrene and Bisphenol A. BPA is known to cause a variety of health effects, including early puberty, heart disease, breast cancer and infertility.

“Cyclodextrin is a very beautiful molecule.  On the outside it’s hydrophobic and on the inside it’s hydrophilic, Hinestroza explained.  It works because of the chemical affinity of the molecule – it is able to capture the pollutants inside and reuse them.

In fact, one of Hinestroza’s main goals is to develop a “super-suit” capable of repelling stains, changing colors and healing minor wounds.  We are also working on clothing that changes colors without pigments.  For example, when there is an allergen close by, the clothing will change colors to alert
you.  If someone spills wine on the clothing, it should be able to repel the stain and scent.

Article from NanoMeter
The Newsletter of the Cornell Nanoscale Facility

nano     nanobots

Herbs and Spices Inhibit AGE

AntiAging

Herbs and Spices Inhibit AGE

The  Journal of Medicinal Food published a report by researchers at the University of Georgia.  It revealed that a number of common herbs and spices offer significant protection against the formation of advanced glycation end-products (AGE). Advanced glycation end-products are the result of the bonding of sugar with protein molecules.  This is a process known as glycation, which increases when blood sugar levels are elevated. AGE compounds activate the immune system, leading to excessive inflammation and tissue damage. This damage can occur in the blood vessel walls, contributing to atherosclerosis.

For the current study, University of Georgia College of Family and Consumer Sciences associate professor James Hargrove and colleagues prepared extracts of 24 herbs and spices purchased at a major supermarket. The extracts were tested for their phenolic content, antioxidant potential, and protein glycation inhibitory activity.

Cloves and cinnamon emerged as the leading spices in phenolic content among the extracts tested. (Phenols are plant compounds which have an antioxidant property) The total phenolic content of cloves was found to be 30 percent of its dry weight, which is significantly higher than blueberries, a food that is known for its antioxidant and phenolic content. The team discovered a strong correlation between the extracts’ phenol content and their ability to block AGE formation. Other extracts which significantly inhibited glycation were Jamaican allspice and apple pie spice, which is a blend of allspice, cinnamon and nutmeg. The remaining herbs and spices, including oregano, rosemary, and turmeric, also showed an ability to inhibit glycation, but at lesser dilutions.

“Because herbs and spices have a very low calorie content and are relatively inexpensive.  They’re a great way to get a lot of antioxidant and anti-inflammatory power into your diet,” Dr Hargrove advised. “Culinary herbs and spices are all generally recognized as safe and have been time-tested in the diet. Some spices and herbals are now sold as food supplements because of their recognized health benefits.”

If you set up a good herb and spice cabinet and season your food liberally, you could double or even triple the medicinal value of your meal without increasing the caloric content.

 

Anti Aging